Bertrand Llorente

The paper quantifies mating strategies in yeast gametes, revealing a reproductive hierarchy where sibling gametes have divergent mating trajectories and temporal heterogeneity shapes compatibility.

The paper identifies a novel mechanism for autopolyploidization in yeast called SEM, demonstrating triploid and tetraploid formation through postmeiotic endoreplication and mating.

The paper shows repeated loss of mating-type switching in yeast led to heterothallism, polyploidy, and increased heterozygosity across diverse environments.

The paper analyzes meiotic recombination landscapes across five yeast species, finding species-specific differences in recombination rates, crossover interference, and hotspot conservation.

This paper investigates how Tel1 interacts with Xrs2 to regulate meiotic DNA break interference and the DNA damage checkpoint in yeast.

The paper shows that absence of Red1 and Hop1 recruitment prevents meiotic recombination on a chromosome arm containing the sex locus in Lachancea kluyveri, affecting genome evolution and fitness.

The paper analyzes meiotic recombination in Lachancea waltii, identifying differences in crossover distribution, LOH events, and recombination hotspots compared to related species.

The paper directly determines meiotic crossovers in fission yeast S. pombe, confirming the absence of crossover interference and revealing co-variation in CO numbers across chromosomes.

RecombineX automates tetrad analysis workflows for meiotic recombination, supporting diverse organisms and genetic backgrounds with simulation and batch processing capabilities.

This study investigates cis- and trans-acting factors influencing break-induced replication (BIR) efficiency, revealing length-dependent properties and the role of Srs2 helicase in different cell types.

The paper shows that mismatch repair (MMR) suppresses meiotic class I crossovers (COs) at regions of high sequence divergence in yeast, linking MMR to CO distribution and speciation.

The paper shows that DNA double-strand breaks (DSBs) during meiosis often occur in clusters with periodic spacing, challenging the idea that DSBs are isolated events.

The paper identifies QTL hotspots in Lachancea waltii for growth fitness and shows they are not conserved in a closely related species.

The paper shows that the Pif1 helicase is inhibited by the Mer3-MutLβ complex during meiotic recombination, limiting gene conversion tract length.

This study investigates the distinct roles of Mec1 and Rad24 in meiotic recombination, showing that Mec1 affects DSB trans-interference and CO pathway distribution, while Rad24 influences interference through CO number reduction.

The paper redesigns a genomic region for improved Hi-C analysis, revealing insights into homolog pairing and loop formation during meiosis.

The paper analyzes meiotic recombination mechanisms by examining heteroduplex DNA tracts and DSB locations, supporting the synthesis-dependent strand annealing model and identifying factors influencing crossover resolution.

The paper examines meiotic recombination differences between Saccharomyces cerevisiae and Lachancea kluyveri, finding significant variations in recombination rates, crossover patterns, and hotspot conservation across evolutionary distances.