Author

Sylvain Legrand

Centre National de la Recherche ScientifiqueORCID 0009-0002-0702-3435Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Anne FriedrichiD· 2 shared Bertrand LlorenteiD· 2 shared Joseph SchachereriD· 2 shared Agnès ThierryiD· 1 shared Amaury Bignaut· 1 shared Arnaud GuilléiD· 1 shared Asma SaifudeeniD· 1 shared Aurore SancheziD· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenetics

Anne FriedrichORCID

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2 papers

Recent·Most cited

Absence of chromosome axis proteins recruitment prevents meiotic recombination chromosome-wide in the budding yeast Lachancea kluyveri

Sylvain Legrand, Asma Saifudeen, Hélène Bordelet, Julien Vernerey, Arnaud Guillé, Amaury Bignaut, Agnès Thierry, Laurent Acquaviva, Maxime Gaudin, Aurore Sanchez, Dominic Johnson, Anne Friedrich, Joseph Schacherer, Matthew J. Neale, Valérie Borde, , Bertrand Llorente

The paper shows that absence of Red1 and Hop1 recruitment prevents meiotic recombination on a chromosome arm containing the sex locus in Lachancea kluyveri, affecting genome evolution and fitness.

bioRxiv · Aug 28, 2023 · PreprintGenetics

Variation Of The Meiotic Recombination Landscape And Properties Over A Broad Evolutionary Distance In Yeasts

Christian Brion, Sylvain Legrand, Jackson Peter, Claudia Caradec, David Pflieger, Jing Hou, Anne Friedrich, Bertrand Llorente, Joseph Schacherer

The paper examines meiotic recombination differences between Saccharomyces cerevisiae and Lachancea kluyveri, finding significant variations in recombination rates, crossover patterns, and hotspot conservation across evolutionary distances.

PLoS Genetics · Aug 1, 2017Peer-reviewedGenomics