Molecular BiologybioRxivPreprint
The ERCC6L2-MRI-KU complex coordinates NHEJ at staggered DNA double-strand breaks.
Pia I. Reichl, Ceylan Sönmez, Yueru Sun…·J. Ross Chapman
The paper identifies the ERCC6L2-MRI-KU complex as a KU-regulatory DNA translocase that coordinates NHEJ at staggered DNA double-strand breaks, linking it to immunodeficiency and haematopoietic failure in ERCC6L2 disease.
1 citation