Author
University of DundeeORCID 0000-0001-5765-0926Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Dylan E. Ramage, Lianne H. E. Wieske, Charlotte Crowe…·Richard T. Timms
The paper identifies LRRC58 as a substrate adaptor in a Cul2 E3 ligase complex that regulates CDO1 degradation in response to cysteine availability, preventing ferroptosis and neurodevelopmental defects.
Valentina A. Spiteri, Dmitri Segal, Alejandro Correa-Sáez…·Georg E. Winter
This study shows that a monovalent MGD can recruit two E3 ligases redundantly to degrade SMARCA2/4, with tunable ligase preference through chemical and genetic modifications.
Ramchandra Vijay Amnekar, Toby A. Dite, Paweł Lis…·Dario R. Alessi
This study identifies NRBP1 as an upstream activator of the WNK pathway by forming a multi-subunit complex with WNK1, SPAK, and TSC22D4 in response to osmotic stress.
Maria Rodriguez-Rios, Conner Craigon, Mark A. Nakasone…·Alessio Ciulli
BromoCatch is a new self-labelling protein tag platform that enables rapid, specific, and stable protein labelling in live cells through covalent ligand engagement.