Leah C. Fuller

A C-terminal motif containing a PKC phosphorylation site regulates γ-Protocadherin-mediated dendrite arborization in the cerebral cortex in vivo

This study shows that phosphorylation of a shared C-terminal motif in γ-Protocadherin negatively regulates dendrite arborization in cortical neurons, with a C-terminal deletion causing the strongest phenotype.

γ-Protocadherins control synapse formation and peripheral branching of touch sensory neurons

This study shows that γ-protocadherin isoforms are critical for synapse formation and peripheral branching in touch sensory neurons, and their loss disrupts corticospinal synapses.

CRISPR/Cas9 interrogation of the mouse Pcdhg gene cluster reveals a crucial isoform-specific role for Pcdhgc4

The paper uses CRISPR/Cas9 to disrupt isoforms of the Pcdhg gene cluster in mice, finding that Pcdhgc4 is the only critical isoform for neuronal function.