H3K27me3 dictates atypical genome-nuclear lamina interactions and allelic asymmetry during early embryogenesis
Isabel Misteli Guerreiro, Franka J. Rang, Yumiko Kawamura, Femke C. Groenveld, Ramada E. van Beek, Silke J. A. Lochs, Ellen Boele, Antoine H.F.M. Peters, Jop Kind
This study identifies H3K27me3's role in regulating genome-nuclear lamina interactions and allelic asymmetry during early mouse embryogenesis through single-cell LAD profiling and chromatin state analysis.
bioRxiv · Feb 6, 2023 · PreprintGenomics