Sofia Anagianni

This paper develops a pipeline to identify and evaluate novel manganese chelators using zebrafish and mouse models, finding that H3PyC3A and Me3PyC3A show improved manganese mobilization and reduced accumulation.

This study shows that rbfox1 loss of function in zebrafish disrupts stress-related gene expression and increases cortisol levels during development, leading to behavioral and physiological signs of allostatic overload in adulthood.

The paper generates zebrafish mutants with fzd9b disruptions to study anxiety and social behaviors linked to Williams syndrome, finding altered stress responses and compensatory gene upregulation.