Adele Leggieri

This study shows that rbfox1 loss of function in zebrafish disrupts stress-related gene expression and increases cortisol levels during development, leading to behavioral and physiological signs of allostatic overload in adulthood.

The paper generates zebrafish mutants with fzd9b disruptions to study anxiety and social behaviors linked to Williams syndrome, finding altered stress responses and compensatory gene upregulation.

This study investigates the behavioral effects of rbfox1 deficiency in zebrafish, finding multiple behavioral changes that resemble those in Rbfox1-deficient mice and psychiatric patients.