Systems BiologyNature CommunicationsPeer-reviewed
Hematopoietic lineages diverge within the stem cell compartment
Mina N.F. Morcos, Congxin Li, Clara M. Munz…·Alexander Gerbaulet
The paper uses fate-mapping, single-cell RNA-sequencing, and computational methods to show that major hematopoietic lineages diverge within HSCs, identifying a self-renewing HSC subpopulation and a direct thrombopoiesis pathway.