Author

Steven de Jong

University Medical Center GroningenORCID 0000-0001-5831-6997Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Arkajyoti BhattacharyaiD· 2 shared Mathilde JalvingiD· 2 shared Rudolf S.N. FehrmanniD· 2 shared Alexander van OudenaardeniD· 1 shared Anna K.L. ReynersiD· 1 shared Carlos G. Urzúa-TraslaviñaiD· 1 shared Clara BonnetiD· 1 shared Daniel DurocheriD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

Arkajyoti BhattacharyaORCID

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3 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedNov 24, 2025

WEE1 inhibitors trigger GCN2-mediated activation of the integrated stress response

Rinskje B. Tjeerdsma, Timothy F. Ng, Maurits Roorda…·Marcel A.T.M. van Vugt

This study shows WEE1 inhibitors trigger the integrated stress response via GCN2 activation, leading to translational shutdown, which can be mitigated by low-dose or combination treatments.

8 citations

humanproteomics

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Cancer BiologyeLifePeer-reviewedMay 13, 2025

Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer

Arkajyoti Bhattacharya, Thijs S Stutvoet, Mirela Perla…·Rudolf S.N. Fehrmann

2 citations

humanbulk RNA-seq

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BioinformaticsbioRxivPreprintOct 1, 2020

Robust and independent metabolic transcriptional components in 34,494 patient-derived samples and cell lines: a resource for translational cancer research

Vincent Christiaan Leeuwenburgh, Carlos G. Urzúa-Traslaviña, Arkajyoti Bhattacharya…·Rudolf S.N. Fehrmann

The paper uses c-ICA on 34,494 bulk expression profiles to define metabolic transcriptional components and their associations with drug sensitivity, patient outcomes, and immune microenvironment.

DOI 10.1101/2020.10.01.321950

humanbulk RNA-seq

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