Author

Rinskje B. Tjeerdsma

University Medical Center GroningenORCID 0009-0000-1175-8333Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alexander van OudenaardeniD· 2 shared Jeroen van den BergiD· 2 shared Marcel A.T.M. van VugtiD· 2 shared Michael A. VanInsbergheiD· 2 shared Alva BiraniD· 1 shared Anja GrothiD· 1 shared Chance C. SineiD· 1 shared Claire ArmstrongiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Alexander van OudenaardenORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedNov 24, 2025

WEE1 inhibitors trigger GCN2-mediated activation of the integrated stress response

Rinskje B. Tjeerdsma, Timothy F. Ng, Maurits Roorda…·Marcel A.T.M. van Vugt

This study shows WEE1 inhibitors trigger the integrated stress response via GCN2 activation, leading to translational shutdown, which can be mitigated by low-dose or combination treatments.

8 citations

humanproteomics

𝕏 PostBluesky

Cell BiologyMolecular CellPeer-reviewedNov 12, 2024

Acute multi-level response to defective de novo chromatin assembly in S-phase

Jan Dreyer, Giulia Ricci, Jeroen van den Berg…·Francesca Mattiroli

This study investigates the acute effects of CAF-1 loss on chromatin assembly during S-phase, revealing multi-level responses including replication slowdown and histone modification changes.

17 citations

humanscRNA-seq

𝕏 PostBluesky