Author
University Medical Center GroningenORCID 0000-0001-8779-4680Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Fia Fia Lie, Maurits Roorda, Maaike Goris…·Robert Henning
This study shows that calorie restriction induces daily torpor in mice, causing DNA damage that is repaired during arousal, and that cooling during arousal inhibits DNA repair.
Adrian Jakubowski-Addabbo, Maarten R. Hamberg, Fia Fia Lie…·Rob H. Henning
The paper identifies stage-specific transcriptional changes in garden dormouse cerebral cortex during hibernation phases, revealing metabolic and redox adaptations and a reversal during arousal.
Rinskje B. Tjeerdsma, Timothy F. Ng, Maurits Roorda…·Marcel A.T.M. van Vugt
This study shows WEE1 inhibitors trigger the integrated stress response via GCN2 activation, leading to translational shutdown, which can be mitigated by low-dose or combination treatments.
Maria F. Suárez Peredo Rodríguez, Laura J. Jilderda, Catalina Gaviria Agudelo…·Floris Foijer
The paper shows that increased PRMT5-MEP50 complex activity helps aneuploid cancer cells survive by reducing protein aggregation and proteotoxicity.
Lin Zhou, Siqi Zheng, Fernando Rodrigo Rosas Bringas…·Floris Foijer
The paper identifies HDAC4 as a synthetic lethal target in MELK-overexpressing cancers through a yeast screen and mammalian validation.