Cancer BiologyCell Reports MedicinePeer-reviewed
Spatial transcriptomics analysis identifies a unique tumor-promoting function of the meningeal stroma in melanoma leptomeningeal disease
Hasan Alhaddad, Oscar E. Ospina, Mariam Lotfy Khaled…·Inna Smalley
This study uses spatial transcriptomics to identify a tumor-promoting role of meningeal stroma in melanoma leptomeningeal disease and shows that targeting SERPINA3 or its downstream pathway can restore drug sensitivity.
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