Author

Inna Smalley

Moffitt Cancer CenterORCID 0000-0002-6796-9145Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Alex C. SoupiriD· 2 shared Anders BerglundiD· 2 shared Brooke L. FridleyiD· 2 shared Kenneth Yee TsaiiD· 2 shared Oscar E. OspinaiD· 2 shared Alex M. JaegeriD· 1 shared Ana P. GomesiD· 1 shared Christopher M. WilsoniD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioinformatics

Alex C. SoupirORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Aging directs the differential evolution of KRAS-driven lung adenocarcinoma

Felicia Lazure, Stanislav Drápela, Xiaoxian Liu, John H. Lockhart, Hossein Kashfi, Nadir Sarigul, Didem Ilter, Elsa Renee Flores, Xuefeng Wang, Inna Smalley, Alex M. Jaeger, Xiaoqing Yu, Ana P. Gomes

This study uses single-cell RNA-sequencing to show that aging promotes KRAS-driven lung adenocarcinoma evolution toward a stem-like state through age-related changes in the tumor microenvironment.

bioRxiv · Jan 20, 2025 · PreprintCancer Biology

spatialGE: A user-friendly web application to democratize spatial transcriptomics analysis

Oscar E. Ospina, Roberto Manjarres-Betancur, Guillermo González-Calderón, Alex C. Soupir, Inna Smalley, Kenneth Yee Tsai, Joseph Markowitz, Ethan J. Vallebuona, Anders Berglund, Steven A. Eschrich, Xiaoqing Yu, Brooke L. Fridley

spatialGE simplifies spatial transcriptomics analysis by providing a user-friendly web interface for non-programmers, enabling tasks like quality control, domain detection, and spatial analysis.

bioRxiv · Jun 27, 2024 · PreprintBioinformatics

spatialGE: Quantification and visualization of the tumor microenvironment heterogeneity using spatial transcriptomics

Oscar E. Ospina, Christopher M. Wilson, Alex C. Soupir, Anders Berglund, Inna Smalley, Kenneth Yee Tsai, Brooke L. Fridley

The paper introduces spatialGE, a software tool for quantifying and visualizing tumor microenvironment heterogeneity using spatial transcriptomics data.

Bioinformatics · Mar 7, 2022Peer-reviewedBioinformatics