Cell BiologybioRxivPreprint
CRISPR-PTM and CRISPR-VEIS: Multiplexed platforms for quantitative functional analysis of endogenous phosphosites
Simon Willaume, Jan Benada, Karen Akopyan…·Claus Storgaard Sørensen
This paper introduces CRISPR-PTM and CRISPR-VEIS to quantitatively analyze endogenous phosphosite effects on cellular fitness and signaling, showing Y19 as a novel inhibitory site in the WEE1-CDK1 pathway.
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