Author

Karen Akopyan

Karolinska Institutet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Arne LindqvistiD· 3 shared Jan BenadaiD· 2 shared Claus Storgaard SørenseniD· 1 shared Erik Mullers· 1 shared Fulya TaylaniD· 1 shared Himjyot Jaiswal· 1 shared Jayashree Vijay Thatte· 1 shared Kamila Burdova· 1 shared

Activity by Year

2016-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCell Biology

Arne LindqvistORCID

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3 papers

Recent·Most cited

Cumulative microscopy reveals cellular states in fibroblasts from patients with genetic disorders

Karen Akopyan, Zhiyu Hao, Susann Karlberg, Svetlana Vakkilainen, Fulya Taylan, Minna Pekkinen, Outi Mäkitie, Arne Lindqvist

The paper introduces cumulative microscopy to analyze cellular states in fibroblasts from patients with genetic disorders, finding replication stress in CHH but not MUL.

EMBO Reports · May 16, 2026Peer-reviewedCell Biology

CRISPR-PTM and CRISPR-VEIS: Multiplexed platforms for quantitative functional analysis of endogenous phosphosites

Simon Willaume, Jan Benada, Karen Akopyan, Valdemaras Petrosius, Jayashree Vijay Thatte, Thomas C. R. Miller, Arne Lindqvist, Claus Storgaard Sørensen

This paper introduces CRISPR-PTM and CRISPR-VEIS to quantitatively analyze endogenous phosphosite effects on cellular fitness and signaling, showing Y19 as a novel inhibitory site in the WEE1-CDK1 pathway.

bioRxiv · May 9, 2026 · PreprintCell Biology

An ATM/Wip1-dependent timer controls the minimal duration of a DNA-damage mediated cell cycle arrest

Himjyot Jaiswal, Jan Benada, Erik Mullers, Karen Akopyan, Kamila Burdova, Tobias Koolmeister, Thomas Helleday, Rene Medema, Libor Macurek, Arne Lindqvist

The paper identifies an ATM/Wip1-dependent timer mechanism that determines the minimal duration of DNA-damage-induced cell cycle arrest.

bioRxiv · Mar 2, 2016Cell Biology