José García‐Martínez

This study shows eIF5A coordinates gene expression by repressing transcription of its target genes in the nucleus while promoting their translation in the cytoplasm.

The paper shows that transcription elongation control and mRNA stability coordinate to regulate gene expression strategies across the yeast cell cycle.

This study investigates how Sfp1 regulates mRNA synthesis and stability by interacting with Pol II and influencing mRNA fate through co-transcriptional binding.

The paper shows that RNA-controlled shuttling of Xrn1 and its decay factors regulates mRNA synthesis and decay, revealing a novel nuclear-initiated cytoplasmic decay pathway.

The paper models how RNA binding proteins can buffer or enhance gene expression by synergistically affecting transcription and mRNA decay rates, supported by analysis of yeast genomic datasets.

The paper shows that cell volume regulates rDNA copy number and RNA polymerase I synthesis rate in yeast through a feedback mechanism involving Sir2.

The paper compares gene expression strategies across four organisms, showing common patterns and phylogenetic relationships based on expression variables.

The paper investigates mRNA buffering in yeast and finds that total mRNA concentration is buffered globally rather than gene-specifically.