Anton J. M. Larsson

RNA BaseCode is a synthetic long-read RNA sequencing method that achieves short-read accuracy and improves full-length transcript reconstruction compared to existing long-read methods.

This study shows transcriptional bursts explain autosomal monoallelic expression and influence allelic imbalance in scRNA-seq data.

This paper introduces Smart-seq3, a single-cell RNA sequencing method that enables allele- and isoform-resolution RNA counting, showing improved sensitivity and isoform regulation detection in mouse and human samples.

The paper analyzes allele-specific scRNA-seq data to show that X-chromosome upregulation in mouse cells occurs through increased transcriptional burst frequency.

NASC-seq monitors newly synthesized RNA in single cells, revealing dynamic gene expression during T-cell activation.

This paper presents a computational method to correct cross-contamination in sequencing data, reducing false positives and spurious clustering by 80-90%.