Geoff Stanley

The paper creates a cell type atlas of the adult murine striatum using single-cell RNA-seq and identifies discrete and continuous cell identities within spiny projection neurons.

This paper presents a computational method to correct cross-contamination in sequencing data, reducing false positives and spurious clustering by 80-90%.

On patterned flow cells using exclusion amplification, up to 5-10% of reads are credited to the wrong sample in a pool, traced to free index primers surviving library cleanup.