Gert‐Jan Hendriks

RNA BaseCode is a synthetic long-read RNA sequencing method that achieves short-read accuracy and improves full-length transcript reconstruction compared to existing long-read methods.

The paper introduces molecular spikes as a gold standard to evaluate RNA counting accuracy in single-cell RNA-sequencing methods.

This study investigates the transcriptional dynamics and functions of long non-coding RNAs using single-cell RNA-seq, revealing distinct burst kinetics and cell-state specific roles.

This study shows transcriptional bursts explain autosomal monoallelic expression and influence allelic imbalance in scRNA-seq data.

The paper characterizes a gene expression oscillator in C. elegans larvae, showing it starts in embryos, arrests transiently, and ceases in adults, operating near a SNIC bifurcation.

This paper introduces Smart-seq3, a single-cell RNA sequencing method that enables allele- and isoform-resolution RNA counting, showing improved sensitivity and isoform regulation detection in mouse and human samples.

NASC-seq monitors newly synthesized RNA in single cells, revealing dynamic gene expression during T-cell activation.