Ilaria Ceppi

The paper demonstrates that satellite DNA barcodes facilitate meiotic pairing in Drosophila by showing that repeat mismatches disrupt pairing and that pairing defects correlate with oocyte death.

This paper shows that IFI16 detects stalled replication forks and triggers an innate immune response, while also protecting nascent DNA from degradation and aiding in fork protection in BRCA-deficient cells.

This study shows that nuclear mechanostability arises from satellite DNA condensation into chromocenters, which help dissipate mechanical stress and protect genome integrity.

This study identifies the PIN1-p38-CtIP signaling pathway as essential for protecting stalled replication forks from degradation, independent of its role in homologous recombination.