Author

Rebecca C. Schugar

Cleveland ClinicORCID 0000-0001-5908-2213Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Justin P. AnnesiD· 2 shared Adam E. MullickiD· 1 shared Amanda L. BrowniD· 1 shared Amy C BurrowsiD· 1 shared Anthony J. HorakiD· 1 shared Anzel Zhen· 1 shared Brian Lim· 1 shared Bryan L. RothiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

Justin P. AnnesORCID

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3 papers

Recent·Most cited

Cancer BiologyEndocrine Related CancerPeer-reviewedFeb 19, 2026

Succinate Dehydrogenase-Deficient Cancer Cells Have Increased Susceptibility to Ym155 Induced DNA Damage

Qianjin Guo, Sooyeon Lee, N. Armstrong…·Justin P. Annes

This paper shows SDHB-deficient cancer cells are more sensitive to Ym155-induced DNA damage due to impaired DNA repair and succinate accumulation.

1 citation

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Cancer BiologybioRxivPreprintJul 29, 2025

The Lipid Hydrolase ABHD6 is a Therapeutic Target in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)-Related Hepatocellular Carcinoma

Danny Orabi, William J. Massey, Kevin K. Fung…·J. Mark Brown

This study identifies ABHD6 as a therapeutic target in MASLD-related HCC by showing its role in lysosomal lipid remodeling and tumor progression.

1 citation

mouseexperimental assay

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Cell BiologybioRxivPreprintMay 1, 2024

An shRNA screen in primary human beta cells identifies the serotonin 1F receptor as a negative regulator of survival during transplant

Rebecca A. Lee, Deeksha Gambhir, Vinh Q Nguyen…·Gregory Ku

The paper identifies the serotonin 1F receptor as a negative regulator of human beta cell survival during transplant and demonstrates a small molecule antagonist that improves glycemia in islet transplants.

DOI 10.1101/2024.05.01.591950

humanproteomics

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