Author

Roman Sobotka

Czech Academy of SciencesORCID 0000-0001-5909-3879Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Developmental Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Assay:DNA methylation· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Andrew HitchcockiD· 1 shared Anna WysockaiD· 1 shared Arman PazukiiD· 1 shared Benoît VanhollebekeiD· 1 shared Berness Peter FalcaoiD· 1 shared Catharina J. M. Langedijk· 1 shared Christopher Neil HunteriD· 1 shared Dmitry ShvareviD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperPlant Biology

Andrew HitchcockORCID

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4 papers

Recent·Most cited

MicrobiologybioRxivPreprintJul 30, 2026

Cyanochelin uptake reveals an exclusively cyanobacterial class of AMIN-domain TonB-dependent transporters

Jan Masek, Berness Peter Falcao, Lucie Grodecká…·Pavel Hrouzek

The paper functionally characterizes a cyanobacterial TonB-dependent transporter for cyanochelin B uptake and shows its specificity and evolutionary link to other siderophore transport systems.

1 citation

experimental assaycell type annotation

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Plant BiologybioRxivPreprintMay 15, 2026

Structure of chlorophyll synthase in complex with the LHC-like protein HliD

Dmitry Shvarev, Anna Wysocka, Felix S. Morey-Burrows…·Roman Sobotka

The paper determines the structure of the ChlG2HliD2 complex using cryo-EM to elucidate chlorophyll synthesis and photoprotection mechanisms.

1 citation

cryo-EMexperimental assay

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MicrobiologyDNA ResearchPeer-reviewedDec 1, 2024

Epigenetic control of tetrapyrrole biosynthesis by m4C DNA methylation in a cyanobacterium

Nils Schmidt, Nils Stappert, Kaori Nimura-Matsune…·Wolfgang R. Hess

The paper shows that m4C DNA methylation regulates hemJ expression in Synechocystis, affecting tetrapyrrole biosynthesis and pigmentation.

3 citations

C. elegansDNA methylation

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Developmental BiologyNature CommunicationsPeer-reviewedNov 18, 2022

Heme-deficient metabolism and impaired cellular differentiation as an evolutionary trade-off for human infectivity in Trypanosoma brucei gambiense

Eva Horáková, Laurence Lecordier, Paula Cunha…·Julius Lukeš

This study identifies heme-deficient metabolism and impaired cellular differentiation as evolutionary trade-offs for human infectivity in Trypanosoma brucei gambiense due to HpHbR inactivation.

3 citations

experimental assay

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