Wolfgang R. Hess

LIGR-Nue for the global mapping of the bacterial sRNA targetome in vivo

The paper introduces LIGR-Nue, a method to map bacterial sRNA targetomes, identifying sRNA functions in post-transcriptional regulation.

The relevance of GGCC methylation for cyanobacterial gene expression regulation

The paper investigates the impact of GGCC methylation on gene expression in Synechocystis 6803 and finds it affects over 300 genes, with context-specific effects on promoter regions.

Inositol phosphates, pyrophosphates and the genes involved in their turnover in the streptophyte green alga Chara braunii

This study identifies a complex inositol phosphate network in the streptophyte alga Chara braunii, showing its structural and environmental responsiveness before land plants evolved.

Deletion of the gene for a cyanobacterial ribosome-associated protein affects the carbon/nitrogen metabolism

This paper characterizes the function of the cyanobacterial gene ssr3189 by analyzing its deletion mutant, revealing its role in linking translation with metabolic control and RNA decay.

A revised genome annotation of the model cyanobacterium Synechocystis based on start and stop codon-enriched ribosome profiling and proteogenomics

This paper revises the genome annotation of Synechocystis using ribosome profiling and proteogenomics, identifying new genes and correcting existing annotations.

Genomic Isomerism and Environmental Adaptation in Cyanophages Infecting Freshwater Cyanobacteria

This study characterizes three cyanophages infecting Anabaena sp. PCC 7120, revealing genomic isomerism, environmental adaptation, and novel gene functions.

The small protein SbtC is a functional component of the CO2 concentrating mechanism of cyanobacteria

The paper identifies SbtC as a small protein involved in the cyanobacterial CO2 concentrating mechanism, showing it forms a trimeric complex with SbtA and SbtB to regulate bicarbonate exchange.

RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics datasets

RAPDOR uses Jensen-Shannon distance to analyze complex proteomics datasets, identifying RNA-binding proteins in cyanobacteria and showing its utility in stress-induced protein redistribution.

The RRM domain-containing protein Rbp3 interacts with ribosomes and the 3' ends of mRNAs encoding photosynthesis proteins

This paper identifies Rbp3 as an RRM domain protein in Synechocystis that binds mRNAs encoding photosynthesis proteins and localizes near ribosomes.

Analysis of tracrRNAs reveals subgroup V2 of type V-K CAST systems

The paper identifies a new subgroup of type V-K CAST systems in cyanobacteria through phylogenetic analysis and characterizes its unique features.

Involvement of RNase J in CRISPR RNA maturation in the cyanobacterium Synechocystis sp. PCC 6803

This study identifies RNase J as a new enzyme involved in crRNA maturation in the type III-Bv CRISPR-Cas system of Synechocystis sp. PCC 6803, working with RNase E and possibly another RNase.

Epigenetic control of tetrapyrrole biosynthesis by m4C DNA methylation in a cyanobacterium

The paper shows that m4C DNA methylation regulates hemJ expression in Synechocystis, affecting tetrapyrrole biosynthesis and pigmentation.

RNA-binding proteins identified by R-DeeP/TripepSVM are involved in heterocyst differentiation

The paper identifies RNA-binding proteins involved in heterocyst differentiation in cyanobacteria using mass spectrometry and bioinformatics, revealing a new master regulator.

Integrative analysis of the salt stress response in cyanobacteria

This study integrates transcriptomic, proteomic, and metabolomic data from Synechocystis sp. PCC 6803 to characterize the salt stress response, identifying key regulatory elements and metabolic changes.

Global analysis of the RpaB regulon based on the positional distribution of HLR1 sequences and comparative differential RNA-Seq data

This paper identifies the RpaB regulon in Synechocystis sp. PCC 6803 by analyzing HLR1 motif positioning and RNA-Seq data, revealing 150+ regulated genes with activation or repression based on HLR1-TSS distance.

Conserved accessory proteins encoded with archaeal and bacterial Type III CRISPR-Cas gene cassettes that may specifically modulate, complement or extend interference activity

The paper identifies 39 new Type III CRISPR-Cas associated gene families using comparative genomics and presents them in an online database.

6S RNA supports recovery from nitrogen depletion in Synechocystis sp. PCC 6803

This study shows that 6S RNA in Synechocystis sp. PCC 6803 aids recovery from nitrogen depletion by regulating sigma factor switching and maintaining photosynthetic activity.