Kun Wang

This study shows that P-cadherin-mediated mechanical forces on mesothelial cells enhance lipid production in ovarian cancer cells, promoting metastasis through lactate-driven lipogenesis.

This paper introduces scSimGCL, a graph contrastive learning framework for scRNA-seq data that improves cell clustering through self-supervised pretraining and high-quality representation learning.

The paper identifies widespread loss-of-function mutations in chicken genomes during evolution and domestication, showing non-random patterns and selection-driven gene loss.