Siwen Wu

The paper compares genome sequences and genetic variations of three eared pheasant species at different altitudes to identify adaptation mechanisms.

HRannot provides an accurate and user-friendly gene annotation pipeline for vertebrate genomes, outperforming existing tools and enabling annotation of both known and novel genes.

The paper identifies widespread loss-of-function mutations in chicken genomes during evolution and domestication, showing non-random patterns and selection-driven gene loss.

The paper annotates four high-quality chicken genomes, identifying over 1,400 missing genes in sub-telomeric regions with high G/C content that were previously absent from reference annotations.

The paper presents a high-quality genome assembly for the white-eared pheasant and related transcriptome and population genetics data.

The paper identifies prevalent false positives and false negatives in STARR-seq data and explores their underlying causes using predicted cis-regulatory modules and cell line data.

The paper identifies 65 novel meiotic and fertility genes in Drosophila melanogaster through RNAi screening, showing their role in infertility and chromosomal nondisjunction.

This study identifies numerous selective sweeps and genes under artificial selection in indigenous and commercial chickens using re-sequencing and statistical analysis.