Author
University College CorkORCID 0000-0001-5913-7093Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Nikita M. Shepelev, Elizaveta A. Razumova, Alexandr I Lavrov…·Maria P. Rubtsova
The paper identifies essential uORFs for cell proliferation in human cell lines and shows their regulatory role through cis-elements and variant disruption.
Alla D. Fedorova, Stephen J. Kiniry, Dmitry E. Andreev…·Pavel V. Baranov
The paper identifies thousands of non-AUG initiated proteoforms in humans and mice, many lacking evolutionary selection evidence, using ribo-seq and phylogenetic analysis.
Darren A Fenton, Michał I. Świrski, Patrick B. F. O’Connor…·John P. Morrissey
The paper identifies diverse genome decoding mechanisms in yeast that generate functionally distinct proteoforms and improves genome annotation.
Darren A Fenton, Stephen J. Kiniry, Martina M. Yordanova…·John P. Morrissey
The paper develops a ribosome profiling protocol for Kluyveromyces marxianus and provides tools for data analysis and sharing.
Gary Loughran, Alexander V. Zhdanov, Maria S. Mikhaylova…·Dmitry E. Andreev
The paper identifies a novel protein, POLGARF, encoded by an overlapping reading frame in POLG mRNA, showing efficient CUG initiation and evolutionary origins via MIR transposition.
Dmitry E. Andreev, Maxim Dmitrievich Arnold, Stephen J. Kiniry…·Pavel V. Baranov
The paper develops a computational model to explain how a single upstream open reading frame (uORF) can upregulate downstream ORF translation during the Integrated Stress Response.