Monocyte Migration Emerges from a Divergent Chemokine Signaling Network
Sean S. So, Alexis Lona, Rina Pokhrel, Alexandra L. Morgan, Mila Saltikova, T M Nguyen, Willow Carretero Chavez, Tony Ngo, Harley Robinson, Cheng Huang, Shankar Raj Devkota, Ram Prasad Bhusal, David Harold Drewry, Joel R. Steele, Ralf B. Schittenhelm, , Martin J. Stone
The paper maps the chemokine-stimulated signal transduction network in monocytic cells and shows that chemotaxis emerges from a divergent signaling network that can be inhibited to block cell migration.
bioRxiv · May 4, 2026 · PreprintSystems Biology