Author

Sean S. So

Monash UniversityORCID 0000-0002-1996-2045Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

Irina KufarevaiD· 2 shared Tony NgoiD· 2 shared Alexandra L. MorganiD· 1 shared Alexis LonaiD· 1 shared Andrey V. IlatovskiyiD· 1 shared Angela M. FinchiD· 1 shared Cheng HuangiD· 1 shared David Harold DrewryiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioinformatics

Irina KufarevaORCID

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2 papers

Recent·Most cited

Pharmacological proximities in the GPCR family discovered using contact-informed amino-acid and binding pocket similarities

Sean S. So, Tony Ngo, Andrey V. Ilatovskiy, Angela M. Finch, RF Riek, Ruben A Abagyan, Nicola J. Smith, Irina Kufareva

This paper introduces GPCR-CoINPocket v2, a method to detect pharmacological similarities in GPCRs using sequence and ligand interaction data, revealing new relationships and aiding drug discovery.

bioRxiv · May 6, 2026 · PreprintBioinformatics

Monocyte Migration Emerges from a Divergent Chemokine Signaling Network

Sean S. So, Alexis Lona, Rina Pokhrel, Alexandra L. Morgan, Mila Saltikova, T M Nguyen, Willow Carretero Chavez, Tony Ngo, Harley Robinson, Cheng Huang, Shankar Raj Devkota, Ram Prasad Bhusal, David Harold Drewry, Joel R. Steele, Ralf B. Schittenhelm, , Martin J. Stone

The paper maps the chemokine-stimulated signal transduction network in monocytic cells and shows that chemotaxis emerges from a divergent signaling network that can be inhibited to block cell migration.

bioRxiv · May 4, 2026 · PreprintSystems Biology