Author

Alexis Lona

University of California San DiegoORCID 0009-0007-6147-3804Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Irina KufarevaiD· 3 shared Alexandra L. MorganiD· 1 shared Andrea BrancaleiD· 1 shared Anny Lam· 1 shared Bobby LuceroiD· 1 shared Carlo BallatoreiD· 1 shared Carlos G. GonzaleziD· 1 shared Carmine VarricchioiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

Irina KufarevaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintJun 29, 2026

Selective knockout of PKA regulatory subunits reveal opposite catalytic and metabolic consequences with implications for Alzheimer's disease

Leigh-Ana M. Rossitto, Tsan Wen Lu, Yuliang Ma…·Susan Serota Taylor

This study shows that knocking out PKA regulatory subunits RI and RII leads to distinct metabolic and phosphorylation changes, with RI KO increasing Tau phosphorylation linked to Alzheimer's disease.

DOI 10.64898/2026.06.26.734839

humanproteomics

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Systems BiologybioRxivPreprintMay 4, 2026

Monocyte Migration Emerges from a Divergent Chemokine Signaling Network

Sean S. So, Alexis Lona, Rina Pokhrel…·Martin J. Stone

The paper maps the chemokine-stimulated signal transduction network in monocytic cells and shows that chemotaxis emerges from a divergent signaling network that can be inhibited to block cell migration.

DOI 10.64898/2026.04.29.721539

proteomicsstatistical model

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MicrobiologybioRxivPreprintOct 7, 2025

Structure-Activity Relationship and Target Investigation of Thiophen-2-yl-Pyrimidines against Schistosoma species

Karol R. Francisco, Bobby Lucero, Darius J. Yohannan…·Conor R. Caffrey

This paper identifies a new class of thiophen-2-yl pyrimidines (TPPs) with improved solubility and potency against Schistosoma species, suggesting novel targets beyond tubulin.

DOI 10.1101/2025.10.07.681061

humanexperimental assay

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