Qu Chen

This study shows that neddylation regulates mitochondrial dynamics and turnover in the adult heart, linking its disruption to cardiomyopathy and heart failure.

This study investigates how horizontal gene transfer of a squalene-hopene cyclase enables lipid metabolism rewiring in fission yeast, allowing adaptation to anoxic environments.

This study identifies RBX2 as a key component of the CRL5 ubiquitin ligase that regulates mitophagy in cardiomyocytes independently of PARKIN, maintaining cardiac homeostasis.

This study uses cryo-EM to determine the structural basis of Fc receptor recognition of immunoglobulin M, identifying binding sites and explaining isotype specificity.