Author

Matthias Lauth

Philipps University of MarburgORCID 0000-0001-5922-5384Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1

Frequent Co-Authors

Amina Othman· 1 shared Anna I. BrichkinaiD· 1 shared Anne L. Ashford· 1 shared Ciarán McDonnelliD· 1 shared David Oxley· 1 shared Eliana StanganelloiD· 1 shared Emma DuncaniD· 1 shared Fatma Aktuna· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Amina Othman

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2 papers

Recent·Most cited

Cell BiologyJournal of Cell SciencePeer-reviewedAug 13, 2026

Phosphoproteomics identifies the DYRK1B protein kinase as a regulator of processing bodies

Anne L. Ashford, Suzan Ber, Miriam Ems…·Simon J. Cook

This study identifies DYRK1B as a regulator of processing body abundance through phosphoproteomics and functional assays.

DOI 10.1242/jcs.265054

humanproteomics

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 20, 2026

Tumor Cell Death Drives Tumor-Promoting IL-6+ iCAF formation via P2X7-activation

Ciarán McDonnell, Valeriya V. Zinina, Amina Othman…·Mark R. Schmitt

The paper shows chemotherapy-induced ATP release from dying pancreatic cancer cells activates P2X7 in stellate cells, promoting IL-6 production and tumor resistance.

DOI 10.64898/2026.03.18.712671

mousebulk RNA-seq

𝕏 PostBluesky