Author

Alex C.Y. Chen

Broad InstituteORCID 0000-0002-8358-5408Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Chang-Yu Chen1 paper

Biology Disciplines

Click to filter author papers

Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Bin WuiD· 1 shared Brian C. MilleriD· 1 shared Cansu YerindeiD· 1 shared Daniela Martinez· 1 shared Debattama R. SeniD· 1 shared Eiji SugiharaiD· 1 shared Elizabeth M. Seider· 1 shared Francesca S. GazzanigaiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenomics

Bin WuORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ImmunologyCellPeer-reviewedJul 29, 2026

CRISPR screens identify targets to rescue age-related T cell dysfunction in cancer

Alex C.Y. Chen, Keely Y. Ji, Cansu Yerinde…·Debattama R. Sen

This study identifies Dusp5 and Zfp219 as key regulators of age-related T cell dysfunction using CRISPR screens and shows their potential as therapeutic targets.

2 citationstop 3%

GenomicsCommunications BiologyPeer-reviewedJun 27, 2022

TAS-Seq: a robust and sensitive amplification method for bead-based scRNA-seq

Shigeyuki Shichino, Satoshi Ueha, Shinichi Hashimoto…·Kouji Matsushima

TAS-Seq improves scRNA-seq by enhancing gene detection and cell-cell interaction analysis in murine and human lung samples compared to existing methods.

47 citations