Robert G. Mealer

The paper integrates social risk factors with genetic risk scores to improve bipolar disorder prediction in the All of Us Research Program, finding social factors have larger effect sizes than genetic risk.

This study identifies disrupted O-GalNAc glycosylation as a mechanism and biomarker for SLC35A2-associated epilepsy using mouse models and human tissue analysis.

The paper investigates the N-glycome changes during neuronal differentiation and finds that brain-specific N-glycans like Man-5 are programmed independently of the transcriptome.

The paper identifies O-GalNAc glycans' spatial enrichment in white matter and their role in regulating nodes of Ranvier through glycoproteomic analysis and functional experiments.

The paper identifies distinct spatial distributions of N-glycans in the mouse brain using lectin-based staining.

This study shows that the schizophrenia-associated SLC39A8 variant A391T alters N-glycosylation in the mouse brain, affecting glycoproteins involved in schizophrenia-related pathways.

The paper analyzes glycosylation patterns in mouse brain regions and sexes, finding reduced complexity and minimal sex differences compared to plasma.