Pharmacology & ToxicologybioRxivPreprint
Rapaprotin is Activated by an Endopeptidase to Disassemble 26S Proteasome
Hanjing Peng, Zufeng Guo, Wei Li Wang…·Jun O. Liu
This paper identifies rapaprotin as a 26S proteasome assembly inhibitor that is activated by PREP to induce apoptosis and synergizes with proteasome inhibitors in cancer cells.
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