Author

Hanjing Peng

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

Jun O. LiuiD· 2 shared Zufeng GuoiD· 2 shared A. V. Subba Rao· 1 shared Alka RaoiD· 1 shared Brett R. Ullman· 1 shared Christian Burris GockeiD· 1 shared Cordelia Schiene‐FischeriD· 1 shared Deyao YiniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

Jun O. LiuORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Identification of Rapaglutin E as An Isoform-specific Inhibitor of Glucose Transporter 1

Marnie Kotlyar, Zufeng Guo, Alka Rao, Hanjing Peng, Jingxin Wang, Zhongnan Ma, Cordelia Schiene‐Fischer, Günter Fischer, Jun O. Liu

This paper identifies rapaglutin E as a specific inhibitor of GLUT1 and explores its binding mechanism compared to rapaglutin A.

ACS Chemical Biology · Apr 14, 2025Peer-reviewedPharmacology & Toxicology

Rapaprotin is Activated by an Endopeptidase to Disassemble 26S Proteasome

Hanjing Peng, Zufeng Guo, Wei Li Wang, Deyao Yin, Shitao Zou, Thomas Asbell, Brett R. Ullman, Maya Thakar, Feiran Zhang, Sam Y. Hong, A. V. Subba Rao, Kunyu Wang, Shuwen Zhang, Zhaolong Wu, Xuemei Li, , Jun O. Liu

This paper identifies rapaprotin as a 26S proteasome assembly inhibitor that is activated by PREP to induce apoptosis and synergizes with proteasome inhibitors in cancer cells.

bioRxiv · Feb 21, 2025 · PreprintPharmacology & Toxicology