Author

Deyao Yin

Peking UniversityORCID 0000-0002-6388-4654Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Shitao ZouiD· 3 shared Youdong Jack MaoiD· 3 shared Miyun ShiiD· 2 shared Shuwen ZhangiD· 2 shared Xin LuoiD· 2 shared Xuemei LiiD· 2 shared A. V. Subba Rao· 1 shared Brett R. Ullman· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersBiochemistry

Shitao ZouORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintMar 11, 2026

UBE3C retrofits the proteasome to enforce degradation of ultra-stable folds

Shitao Zou, Deyao Yin, Miyun Shi…·Youdong Jack Mao

This study reveals how UBE3C reprograms the proteasome to degrade ultra-stable protein folds by bypassing USP14 and enhancing substrate unfolding.

DOI 10.64898/2026.02.24.707655

humanprotein structure

𝕏 PostBluesky

BiochemistrybioRxivPreprintFeb 10, 2026

Differential higher-order superassembly of HECT-type UBE3 ligases controlled by calcium signals

Xin Luo, Miyun Shi, Jiao Hu…·Youdong Jack Mao

The paper determines cryo-EM structures of UBE3B and UBE3C in complex with calmodulin, showing how calcium signaling controls their higher-order assembly and activity.

1 citation

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Pharmacology & ToxicologybioRxivPreprintFeb 21, 2025

Rapaprotin is Activated by an Endopeptidase to Disassemble 26S Proteasome

Hanjing Peng, Zufeng Guo, Wei Li Wang…·Jun O. Liu

This paper identifies rapaprotin as a 26S proteasome assembly inhibitor that is activated by PREP to induce apoptosis and synergizes with proteasome inhibitors in cancer cells.

2 citations

humanproteomics

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