Author
Tokyo University of Agriculture and Technology
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
Keita Sawai, Yoshimasa Todoroki, Shohei Nakamukai, Yuki Matsuzawa, Keiichi Noguchi, Toshiyo Kato, Tetsuya Mori, Amit Rai, Masami Yokota Hirai, Hiroshi Tsugawa
The paper uses stable isotope-assisted mass spectrometry to identify root-specific alkaloids in Glycyrrhiza species and proposes their biosynthetic pathway.
bioRxiv · May 8, 2026 · PreprintBiochemistry
Antonino Asaro, Gregor P. Jose, Ilias Gkikas, Sarah Salame, Pauline Perne, Jean Andrea Maillat, Sylvia Ho, Océane Buvry, Lucile Fleuriot, Eva Bastida‐Martínez, Jeremy Vicencio, Julián Cerón, Yuki Matsuzawa, Frédéric Brau, Julie Cazareth, , 武士 原山
This study shows that ether lipid remodeling during neuronal differentiation prevents ferroptosis by balancing pro- and anti-ferroptotic effects through vinyl ether bonds.
bioRxiv · May 6, 2026 · PreprintCell Biology
Yuki Matsuzawa, Kanako Tokiyoshi, Bujinlkham Buyantogtokh, Takaki Oka, Rana Yamamoto, Lu Deng, Gordana Ivosev, David Cox, Paul R.S. Baker, Anjali Chelur, Nic Bloomfield, Manami Takeuchi, Ushio Takeda, Mikiko Takahashi, Mayu Hasegawa, , Hiroshi Tsugawa
The paper introduces ZT Scan DIA, a metabolomics method improving annotation rates and isomer quantification in complex mixtures, with results validated in human plasma and mouse liver tissues.
bioRxiv · Aug 20, 2025 · PreprintBioengineering
Yuto Kurizaki, Yuki Matsuzawa, Mikiko Takahashi, Hiroaki Takeda, Mayu Hasegawa, Makoto Arita, Junki Miyamoto, Hiroshi Tsugawa
This study develops a LC-SWATH-EAD-MS/MS method to deeply characterize FAHFAs in mouse fecal samples, identifying multiple structural variants and age-related changes.
Analytical Chemistry · Apr 4, 2025Peer-reviewedBiochemistry
Hiroaki Takeda, Yuki Matsuzawa, Manami Takeuchi, Mikiko Takahashi, Kozo Nishida, 武士 原山, Yoshimasa Todoroki, Kuniyoshi Shimizu, Nami Sakamoto, Takaki Oka, Masashi Maekawa, Mi Hwa Chung, Yuto Kurizaki, Saki Kiuchi, Kanako Tokiyoshi, , Hiroshi Tsugawa
The paper introduces MS-DIAL 5, a tool for analyzing multimodal mass spectrometry data to elucidate lipid structures and localization using structural annotations.
Nature Communications · Nov 28, 2024Peer-reviewedBioinformatics
Nami Sakamoto, Takaki Oka, Yuki Matsuzawa, Kozo Nishida, J. Jayashankar, Aya Hori, Makoto Arita, Hiroshi Tsugawa
MS2Lipid predicts lipid subclasses from MS/MS data using machine learning, achieving high accuracy and outperforming existing tools.
Metabolites · Nov 7, 2024Peer-reviewedBioinformatics
Kanako Tokiyoshi, Yuki Matsuzawa, Mikiko Takahashi, Hiroaki Takeda, Mayu Hasegawa, Junki Miyamoto, Hiroshi Tsugawa
The paper proposes a hybrid LC-MS/MS approach combining data-dependent and data-independent acquisitions to improve lipid annotation in fast untargeted lipidomics.
Analytical Chemistry · Jan 11, 2024Peer-reviewedBioinformatics
Alan K. Jarmusch, Allegra T. Aron, Daniel Petras, Vanessa V. Phelan, Wout Bittremieux, Deepa D. Acharya, Mohammed M. A. Ahmed, Anelize Bauermeister, Matthew J. Bertin, Paul D. Boudreau, Ricardo M. Borges, Benjamin P. Bowen, Christopher J. Brown, Fernanda O. Chagas, Kenneth D. Clevenger, , Mingxun Wang
MassQL, an open-source query language, lets users search raw mass spectrometry data from any vendor for isotope, fragmentation and neutral-loss patterns, from one file to entire public repositories.
bioRxiv · Aug 6, 2022 · PreprintBioinformatics✦ In-depth digest