Lori A. Setton

This paper develops a microfluidic platform to model sensory neuron-intervertebral disc crosstalk by combining biochemical and electric-field stimulation.

This study tracks the temporal changes in chemokine production and neurovascular invasion in mouse intervertebral discs during degeneration following injury.

This study shows that VEGFA drives neurovascular invasion in degenerating intervertebral discs and contributes to chronic low back pain, with its inhibition preventing pain behaviors.

This study shows that IGF-1 peptide mimetics functionalized on hydrogels enhance MSC survival and reduce inflammation in human intervertebral disc cells.