Remy E. Walk

This study shows that modulating RAGE through genetic or pharmacologic means can reverse diabetes-induced bone impairments across multiple scales.

This study tracks the temporal changes in chemokine production and neurovascular invasion in mouse intervertebral discs during degeneration following injury.

This study uses single-cell RNA sequencing to analyze changes in cell function and maturation in the intervertebral disc after injury, identifying key cell populations and pathways involved in degeneration.

This study shows that VEGFA drives neurovascular invasion in degenerating intervertebral discs and contributes to chronic low back pain, with its inhibition preventing pain behaviors.

This study examines how RAGE signaling and Type 2 Diabetes affect cortical bone mechanics, structure, and material properties in mice, showing sex-specific improvements with RAGE ablation.

This study identifies sex-specific immune cell responses following intervertebral disc injury, revealing differential recruitment of gamma-delta T cells in female mice and NKT cells in males.