Author

Rolf Breinbauer

Graz University of TechnologyORCID 0000-0001-6009-7359Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Achim LassiD· 1 shared Anita Pirchheim· 1 shared Carina WagneriD· 1 shared Clara ZittaiD· 1 shared Clemens HofmanniD· 1 shared Dagmar KratkyiD· 1 shared Dominik BulfoniD· 1 shared Dominik GrossiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

Achim LassORCID

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2 papers

Recent·Most cited

BiochemistryChemical CommunicationsPeer-reviewedJan 1, 2026

Hydrophobic pocket engineering of arylmalonate decarboxylase expands its substrate scope towards the synthesis of the (R)-enantiomers of sterically hindered carboxylic acids

Elske van der Pol, Lisa-Marie Krammer, J. Eder…·Robert Kourist

This study modifies arylmalonate decarboxylase to expand its substrate scope for synthesizing (R)-enantiomers of sterically hindered carboxylic acids with high enantiopurity.

DOI 10.1039/d6cc02837c

experimental assayprotein folding & dynamics

𝕏 PostBluesky

BiochemistrybioRxivPreprintDec 20, 2025

CLN8 enables a non-canonical phospholipid synthesis pathway

Johannes Breithofer, Nermeen Fawzy, Clara Zitta…·Robert Zimmermann

The paper describes a non-canonical phospholipid synthesis pathway catalyzed by CLN8, leading to BMP synthesis and revealing its role in lysosomal lipid homeostasis and Batten disease.

2 citations

humanmouse

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