Daniel L. Hartl

Cellular and molecular basis of PfCoronin function in artemisinin resistance in Plasmodium falciparum

This study identifies PfCoronin's role in artemisinin resistance by showing mutations impair hemoglobin uptake and modulate drug susceptibility during the ring stage of Plasmodium falciparum.

MalKinID: A Likelihood-Based Model for Identifying Malaria Parasite Genealogical Relationships Using Identity-by-Descent

MalKinID identifies malaria parasite genealogical relationships using IBD proportions and segment distributions, showing high accuracy in outcrossed importations but reduced performance in inbreeding scenarios.

Universal signatures of transposable element compartmentalization across eukaryotic genomes

The paper identifies universal patterns of transposable element (TE) compartmentalization across eukaryotic genomes, linking TEs to gene families under selective pressure and adaptive functions.

Proteostasis environment shapes higher-order epistasis operating on antibiotic resistance

The paper investigates how proteostasis machinery influences higher-order epistasis in antibiotic resistance traits across different bacterial species.

De Novo Mutations Resolve Disease Transmission Pathways in Clonal Malaria

This study detects de novo mutations in Plasmodium falciparum to reconstruct disease transmission pathways and identify clade expansions not detectable with previous methods.