Author

Daniela Samaniego‐Castruita

Northwestern UniversityORCID 0000-0001-6082-6603Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Anjana RaoiD· 2 shared Ferhat AyiD· 2 shared Vipul ShuklaiD· 2 shared Abhijit ChakrabortyiD· 1 shared Arlet Lara-Custodio· 1 shared Atsushi OnoderaiD· 1 shared Bruno Villalobos Reveles· 1 shared Bryce Williams· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Anjana RaoORCID

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3 papers

Recent·Most cited

Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedMay 27, 2026

CTCF directly binds G-quadruplex structures to regulate genome topology and gene expression

Daniela Samaniego‐Castruita, Isabella Han, Roxroy C. Morgan…·Vipul Shukla

This study identifies CTCF as a strong G4 DNA binder and shows its role in genome topology and gene expression through chromatin looping and CTCF occupancy.

4 citations

mouseDNA methylation

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Cell BiologyMolecular CellPeer-reviewedDec 1, 2025

Rate Limiting Enzymes in Nucleotide Metabolism Synchronize Nucleotide Biosynthesis and Chromatin Formation

Shashank Srivastava, Daniela Samaniego‐Castruita, Shubhi Srivastava…·Daniel R. Foltz

This study identifies PRPS-PRPSAP complexes as regulators of histone chaperone interactions, linking nucleotide biosynthesis to chromatin assembly.

6 citations

humanproteomics

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ImmunologybioRxivPreprintAug 29, 2025

Loss of TET function in T regulatory cells yields ex-Treg cells biased toward T follicular helper cells, causingautoimmune diseases through autoantibody production

Kazumasa Suzuki, Leo J. Arteaga-Vazquez, Bruno Villalobos Reveles…·Anjana Rao

This study shows that loss of TET function in Treg cells leads to ex-Treg cells that differentiate into Tfh cells, promoting autoantibody production and autoimmune disease.

1 citation

mousebulk RNA-seq

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