Sarah Elizabeth Albritton

The paper shows that condensin DC spreads from rex sites to form TADs on the X-chromosome in C. elegans, but not on autosomes unless rex sites are artificially added.

The paper shows that increased gene dosage in C. elegans leads to increased mRNA expression, indicating no genome-wide dosage compensation mechanism at the mRNA level.

The paper shows that DCC binding reduces active histone modifications at X chromosome gene regulatory elements, fine-tuning X transcription.