Jun Kim

This study shows TFIIIC regulates SMC complex binding and 3D DNA contacts between tRNA genes independently of RNA Pol III.

The paper presents a spatial omics framework combining protein and RNA imaging with machine learning to classify brain cell types and discover structural features at tissue scale.

This study shows that X chromosome dosage compensation mechanisms evolved independently in two nematode lineages through parallel evolution of SMC complexes.

This study investigates cohesin's role in organizing 3D DNA contacts around active enhancers in C. elegans, revealing cohesin-dependent 'fountains' and differences in processivity compared to mammals.

This paper introduces cycleHCR technology for high-resolution spatial transcriptomics and protein imaging in thick tissues, demonstrating its application in mouse embryos and brain slices.

This study shows that topoisomerases I and II regulate condensin DC translocation on the X chromosome in C. elegans, with TOP-2 affecting long-range movement and TOP-1 affecting short-range movement, both essential for gene repression.

The paper shows that condensin DC spreads from rex sites to form TADs on the X-chromosome in C. elegans, but not on autosomes unless rex sites are artificially added.