Author
Virginia Commonwealth UniversityORCID 0000-0001-6103-5168Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Mandy Meijer, Marieke Klein, Doretta Caramaschi…·Edwin J. C. G. van den Oord
This study identifies cell type-specific DNA methylation associations with childhood ADHD symptoms using deconvolution and sequencing-based methylation data from peripheral and cord blood.
Edwin J. C. G. van den Oord, Jerry Guintivano, Karolina A. Åberg
This paper introduces a robust E/TWAS method that improves reproducibility by reducing false discoveries from outliers and artefacts, with minimal power loss and potential increased power in the presence of outliers.
Edwin J. C. G. van den Oord, Karolina A. Åberg
The paper develops a method to deconvolute cell-type effects from bulk brain data using a reference panel of single-nucleus RNA-seq data, showing it can accurately estimate cell-type proportions and perform TWAS for rare cell-types.
Mahdi Moqri, Andrea Cipriano, Daniel C. Nachun…·Vittorio Sebastiano
The paper identifies PRC2 low-methylated regions as a universal biomarker of aging and rejuvenation, showing they account for most age-related DNA methylation gain across tissues.
Robin F. Chan, Gustavo Turecki, Andrey A. Shabalin…·Edwin J. C. G. van den Oord
This study identifies novel methylation associations with major depressive disorder using cell-type-specific methylome-wide association studies in brain and blood samples.