Author

Carlos Vela‐Rodríguez

University of OuluORCID 0000-0001-6123-1003Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Lari LehtiöiD· 2 shared Anna Tuovinen· 1 shared Bernhard LüscheriD· 1 shared Bukunmi Adediran· 1 shared Heli I. Hentilä· 1 shared Johan PääkköneniD· 1 shared Lea Hirschen· 1 shared M. Kristian KoskiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Lari LehtiöORCID

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2 papers

Recent·Most cited

BiochemistryFEBS JournalPeer-reviewedOct 5, 2026

Dimerization of human PARP15 is required for NAD+ binding and automodification

Anna Tuovinen, Johan Pääkkönen, Mirko M. Maksimainen…·Lari Lehtiö

This study shows that dimerization of PARP15 is necessary for NAD+ binding and automodification, supported by structural and biochemical evidence.

DOI 10.1111/febs.70758

humanproteomics

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Molecular BiologyScientific ReportsPeer-reviewedMay 17, 2026

Targeting collagen biosynthesis by small molecules inhibiting the function of the peptide-substrate-binding domain of collagen prolyl 4-hydroxylases

Bukunmi Adediran, Carlos Vela‐Rodríguez, Sudarshan Murthy…·M. Kristian Koski

The paper develops a FRET-based assay to identify small molecules that inhibit collagen prolyl 4-hydroxylases by targeting their peptide-substrate-binding domain, leading to the discovery of a selective inhibitor.

DOI 10.1038/s41598-026-53109-y

experimental assaydrug response / drug discovery

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