Author

Bowen Xu

University of HoustonORCID 0000-0001-6127-7386Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Aniket S. JoshiiD· 2 shared Ashok KumariD· 2 shared Meiricris Tomaz da SilvaiD· 2 shared Ravi Kumar SinghiD· 1 shared Silin Liu· 1 shared Tuan Anh VuongiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Aniket S. JoshiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell BiologyJCI InsightPeer-reviewedJan 27, 2026

Fiber-type vulnerability and proteostasis reprogramming in skeletal muscle during pancreatic cancer cachexia

Bowen Xu, Aniket S. Joshi, Meiricris Tomaz da Silva…·Ashok Kumar

This study identifies molecular mechanisms of skeletal muscle wasting in pancreatic cancer cachexia using snRNA-seq and bulk RNA-seq, revealing transcription factor activity and potential therapeutic targets.

4 citationstop 3%

mousescRNA-seq

𝕏 PostBluesky

PhysiologyEMBO Molecular MedicinePeer-reviewedNov 17, 2025

✦ In-depth digest

Targeting the canonical ER stress IRE1α/XBP1 pathway counteracts pancreatic cancer-induced skeletal muscle wasting

Aniket S. Joshi, Meiricris Tomaz da Silva, Tuan Anh Vuong…·Ashok Kumar

Muscle-specific XBP1 deletion or IRE1α inhibition with 4μ8C preserves muscle mass and strength in KPC pancreatic cachexia mice, curbing proteolysis, STAT3 signaling and fatty acid oxidation.

9 citations

mousebulk RNA-seq

𝕏 PostBluesky