Author

Tuan Anh Vuong

University of HoustonORCID 0000-0002-5162-1953Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Aniket S. JoshiiD· 2 shared Ashok KumariD· 2 shared Meiricris Tomaz da SilvaiD· 2 shared Bin Guo· 1 shared Bowen XuiD· 1 shared Meghana V. TrivediiD· 1 shared Phuong Thi Bich HoiD· 1 shared Ravi Kumar SinghiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

Aniket S. JoshiORCID

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2 papers

Recent·Most cited

Cancer BiologyCommunications BiologyPeer-reviewedMay 6, 2026

Targeting the IRE1α-XBP1 signaling axis impairs tumor growth and promotes myogenic differentiation in rhabdomyosarcoma

Tuan Anh Vuong, Aniket S. Joshi, Phuong Thi Bich Ho…·Ashok Kumar

This study shows that inhibiting the IRE1α-XBP1 signaling pathway reduces tumor growth and promotes differentiation in rhabdomyosarcoma.

2 citations

humanbulk RNA-seq

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PhysiologyEMBO Molecular MedicinePeer-reviewedNov 17, 2025

✦ In-depth digest

Targeting the canonical ER stress IRE1α/XBP1 pathway counteracts pancreatic cancer-induced skeletal muscle wasting

Aniket S. Joshi, Meiricris Tomaz da Silva, Tuan Anh Vuong…·Ashok Kumar

Muscle-specific XBP1 deletion or IRE1α inhibition with 4μ8C preserves muscle mass and strength in KPC pancreatic cachexia mice, curbing proteolysis, STAT3 signaling and fatty acid oxidation.

9 citations

mousebulk RNA-seq

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