Author

Dennis Eng Kiat Tan

The University of Western AustraliaORCID 0000-0001-6149-5084Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Christian Maximilian NefzgeriD· 1 shared Christian PfluegeriD· 1 shared Ethan FordiD· 1 shared Jahnvi PfluegeriD· 1 shared Jose Maria PoloiD· 1 shared Ryan ListeriD· 1 shared Tessa SwainiD· 1 shared Trung Viet NguyeniD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperMolecular Biology

Christian Maximilian NefzgerORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivFeb 15, 2018

A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs

Christian Pflueger, Dennis Eng Kiat Tan, Tessa Swain…·Ryan Lister

This paper develops a modular dCas9-SunTag DNMT3A system to improve DNA methylation editing specificity and reduce off-target effects compared to direct fusion constructs.

188 citations

humanDNA methylation

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